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SKLB188

SKLB188 is an orally active and potent epidermal growth factor receptor (EGFR) inhibitor (IC50=5 nM). SKLB188 suppresses MEK/Erk and Akt/mTOR signaling pathways to inhibit head and neck squamous cell carcinoma (HNSCC) proliferation and induce caspase-dependent apoptosis. SKLB188 is promising for research of EGFR-overexpressing solid tumors.

For research use only. We do not sell to patients.

  • CAS No.: 1350545-09-3
  • Formula: C27H31N9O2
  • Molecular Weight:513.59
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SKLB188 Chemical Structure
    SKLB188 Chemical Structure
CAS No.: 1350545-09-3
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All EGFR Isoforms

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100 mg

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  • SKLB188 Chemical Structure
    SKLB188 Chemical Structure
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  • SKLB188