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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
SM5887
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "SM5887" in MCE Product Catalog:
Cat. No.: HY-B0067
CAS No.: 110267-81-7
Synonyms: SM-5887
Target:
Research Areas:
Amrubicin (SM-5887) is a DNA topoisomerase II inhibitor, used for the research of cancer.
Cat. No.: HY-B0067A
CAS No.: 110311-30-3
Synonyms: SM-5887 hydrochloride
Target:
Research Areas:
Amrubicin (SM-5887) hydrochloride is a DNA topoisomerase II inhibitor, used for the research of cancer.
Cat. No.: HY-B0067B
CAS No.: 92395-36-3
Synonyms: (R)-SM-5887
Target:
Research Areas:
(R)-Amrubicin ((R)-SM-5887) is an anthracycline that effectively treats lung cancer by intercalating into DNA and inhibiting topoisomerase II activity, which consequently hampers DNA replication as well as RNA and protein synthesis, leading to cell growth inhibition and apoptosis. This compound exhibits superior anti-tumor efficacy compared to traditional anthracycline drugs while lacking the cumulative cardiac toxicity typically associated with this drug class.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
