1 Result for "

SMA-12b

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SMA-12b" in MCE Product Catalog:

Cat. No.: HY-137007
CAS No.: 1496553-39-9
Target:  

Interleukin Related

Research Areas:  

Others Inflammation/Immunology

SMA-12b is a small molecule analogue of the parasitic worm compound ES-62. SMA-12b has immunomodulatory activity, acting by regulating the expression of multiple inflammatory response genes, especially those associated with inflammatory bodies. SMA-12b significantly reduces the expression of cytokine IL-1β associated with inflammatory bodies and inhibites the production of IL-1β through a mechanism mediated by NRF2. SMA-12b can be used in the study of rheumatoid arthritis (RA) and other autoimmune diseases .
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