1 Result for "

SRG-II-19F

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SRG-II-19F" in MCE Product Catalog:

Cat. No.: HY-153573
Synonyms: dCym-JQ1
Research Areas:  

Infection

SRG-II-19F (dCym-JQ1) is a BRDTBD1 PROTAC degrader. Its dCym moiety at one end binds to the N-terminal domain of ClpC1 (ClpC1NTD), while its JQ1 moiety at the other end binds to bromodomain 1 of BRDT (BRDTBD1). This molecule induces the degradation of BRDTBD1 by recruiting the BRDTBD1 substrate to the ClpC1P1P2 protease complex. SRG-II-19F serves as a research tool for studies related to mycobacterial protein degradation .
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