1 Result for "

SRI42127

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SRI42127" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-148853
CAS No.: 2727872-68-4
Purity:  99.80%
Target:  

HuR

Research Areas:  

Others

SRI-42127 is a HuR translocation inhibitor. HuR is an RNA regulator that binds to AREs, and HuR translocations promote the production of inflammatory cytokines in glial cells. However, SRI-42127 can destroy mRNA stability and inhibit gene promoter activation. SRI-42127 also inhibits microglial cell activation and attenuates recruitment/chemotaxis of neutrophils and monocytes .
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