1 Result for "

SSTN92-119

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SSTN92-119" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P5133
CAS No.: 1259384-47-8
Synonyms: SSTN92-119
Target:  

Integrin

Research Areas:  

Cancer

Synstatin (92-119) is an inhibitor of αvβ3/αvβ5 integrins and IGF1R with anti-angiogenic, anti-proliferative, antioxidant and anti-tumor activities. Synstatin (92-119) competitively blocks the capture of αvβ3/αvβ5 integrins and IGF1R by syndecan-1, disrupts the formation of the syndecan-1 : integrin : IGF1R ternary complex, inhibits integrin activation and talin-mediated signaling pathways, and blocks VEGF-induced angiogenesis. Synstatin (92-119) is applicable to research related to cancer and hepatocellular carcinoma .
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