1 Result for "

STAT3-IN-20

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "STAT3-IN-20" in MCE Product Catalog:

Cat. No.: HY-155982
CAS No.: 2768427-54-7
Purity:  99.83%
Target:  

STAT

Research Areas:  

Cancer

STAT3-IN-20 (Compound 40) is a selective STAT3 inhibitor (IC50: 0.65 μM). STAT3-IN-20 binds the SH2 domain to inhibit STAT3 phosphorylation, translocation, and downstream gene transcription. STAT3-IN-20 exhibits antiproliferative activities against STAT3-overactivated DU145 and MDA-MB-231 cancer cells (IC50: 2.97 μM and 3.26 μM respectively). STAT3-IN-20 induces cell cycle arrest and apoptosis .
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