1 Result for "

STAT3-IN-49

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "STAT3-IN-49" in MCE Product Catalog:

Cat. No.: HY-179468
Target:  

STAT

Research Areas:  

Cancer

STAT3-IN-49 (compound B16) is a potent and selective STAT3 inhibitor. STAT3-IN-49 binds to the SH2 domain of STAT3, thereby suppressing its phosphorylation and nuclear translocation. STAT3-IN-49 inhibits triple-negative breast cancer (TNBC) cell migration, invasion, and colony formation. STAT3-IN-49 inhibits tumor growth in an MDA-MB-231 xenograft mouse model. STAT3-IN-49 can be used for TNBC research .
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