STAT3-IN-49

STAT3-IN-49 (compound B16) is a potent and selective STAT3 inhibitor. STAT3-IN-49 binds to the SH2 domain of STAT3, thereby suppressing its phosphorylation and nuclear translocation. STAT3-IN-49 inhibits triple-negative breast cancer (TNBC) cell migration, invasion, and colony formation. STAT3-IN-49 inhibits tumor growth in an MDA-MB-231 xenograft mouse model. STAT3-IN-49 can be used for TNBC research.

For research use only. We do not sell to patients.

  • Formula: C21H19N3O5
  • Molecular Weight:393.39
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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