STAT3-IN-49
STAT3-IN-49 (compound B16) is a potent and selective STAT3 inhibitor. STAT3-IN-49 binds to the SH2 domain of STAT3, thereby suppressing its phosphorylation and nuclear translocation. STAT3-IN-49 inhibits triple-negative breast cancer (TNBC) cell migration, invasion, and colony formation. STAT3-IN-49 inhibits tumor growth in an MDA-MB-231 xenograft mouse model. STAT3-IN-49 can be used for TNBC research.
For research use only. We do not sell to patients.
- Formula: C21H19N3O5
- Molecular Weight:393.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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STAT3 |
Chemical Information
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Molecular Weight 393.39
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Formula C21H19N3O5
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SMILES
O=C(C1=C2ON=C1C3=CC=C(OCCN4CCNCC4)C=C3)C5=C(C2=O)C=CO5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)