1 Result for "

STING M155

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "STING M155" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-174136
Target:  

STING IFNAR

Research Areas:  

Inflammation/Immunology

STING Degrader-2 is an orally active STING degrader that promotes proteasome-independent degradation of STING. STING Degrader-2 inhibits cGAMP-induced STING activation, suppresses STING oligomerization, and inhibits phosphorylation of STING and interferon regulatory factor 3 (IRF3). STING Degrader-2 reduces serum IFN-β and CXCL-10 levels in a cGAMP-induced autoimmune disease mouse model. STING Degrader-2 can be used for the research of autoimmune diseases .
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