1 Result for "

SZM679

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SZM679" in MCE Product Catalog:

Cat. No.: HY-151873
CAS No.: 3027645-52-6
Purity:  99.59%
Target:  

RIP kinase

Research Areas:  

Inflammation/Immunology Cancer

SZM679 is a potent, orally active and selective RIPK1 inhibitor with Kd values of 8.6 nM and >5000 nM for RIPK1 and RIPK3, respectively. SZM679 reverses the tumor necrosis factor-induced systemic inflammatory response. SZM679 decreases the Tau hyperphosphorylation, neuroinflammation, and the RIPK1 phosphorylation level in the hippocampus and cortex. SZM679 can be used in research of Alzheimer's disease (AD) .
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