1 Result for "

Scio323

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Scio323" in MCE Product Catalog:

Cat. No.: HY-167679
CAS No.: 309913-51-7
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Scio-323 is an orally available p38 mitogen-activated protein kinase (MAPK) inhibitor with the potential to inhibit chronic inflammatory responses associated with polyethylene particles. Scio-323's oral inhibition pattern had a minimal effect on bone formation. Scio-323 administration inhibited net bone formation after the establishment of a chronic inflammatory response to polyethylene particles. Osteoblast-like activity remained low in all cases of Scio-323 inhibition. Scio-323 failed to improve bone growth in the presence of polyethylene particles .
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