1 Result for "

Ser797

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ser797" in MCE Product Catalog:

Cat. No.: HY-183277
CAS No.: 3088042-00-3
Target:  

EGFR p38 MAPK Akt Apoptosis

Research Areas:  

Cancer

EGFR-IN-209 (Compound 6g) is an orally active, selective EGFR Del19/T790M/C797S inhibitor with an IC50 of 0.056 μM. EGFR-IN-209 blocks the phosphorylation of EGFR and its downstream effector molecules (pMAPK, pAKT). EGFR-IN-209 induces Apoptosis. EGFR-IN-209 exhibits antitumor activity against Osimertinib (HY-15772)-resistant non-small cell lung cancer. EGFR-IN-209 can be used in research related to non-small cell lung cancer .
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