1 Result for "

Sera2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Sera2" in MCE Product Catalog:

Art. -Nr.: HY-153468
CAS. Nr.: 3035547-78-2
Synonyms: TEQ103; Sera2
Forschungsgebiete:  

Cancer

ErSO-TFPy (TEQ103) is an ERα+ tumor cell inhibitor with low nanomolar cytotoxic activity against ERα+ breast cancer cells. ErSO-TFPy activates the sodium channel TRPM4, causes an imbalance of intracellular calcium and sodium ions. ErSO-TFPy dysregulates calcium homeostasis in ERα+ tumor cells, triggers the anticipatory unfolded protein response, and induces rapid immune cell-independent necrotic cell death. ErSO-TFPy can be used for the research of estrogen receptor alpha positive breast cancer [2].
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