1 Result for "

Soclenicant

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Soclenicant" in MCE Product Catalog:

Cat. No.: HY-172236
CAS No.: 1020634-41-6
Synonyms: BNC210; IW-2143
Target:  

nAChR

Research Areas:  

Neurological Disease

Soclenicant (BNC210) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. Soclenicant exhibits acute anxiolytic activity in rodent models of anxiety. Soclenicant inhibits rat and human α7 nAChR currents (in stably transfected cell lines) induced by acetylcholine, nicotine, choline, and the a7-specific agonist PNU-282987 (HY-12560A) with IC50 values in the range of 1.2 to 3 μM. Soclenicant can be used in studies of anxiety, trauma, and stressor-related disorders .
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