1 Result for "

TD114-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TD114-2" in MCE Product Catalog:

Cat. No.: HY-136679
CAS No.: 436866-52-3
Target:  

GSK-3

TD114-2 (cmpound 29) is a potent and highly selective inhibitor of glycogen synthase kinase-3β (GSK-3β) (IC50=48 nM). TD114-2 is associated with the hydrogen bond formation of arginine 141 (ARG141) specific to GSK-3β, an amino acid that is often a negatively charged residue in other kinases, which determines the high selectivity of GSK-3β. TD114-2 can be used in the study of diabetes, neurodegenerative diseases and other diseases associated with GSK-3β .
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