1 Result for "

TDP665759

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TDP665759" in MCE Product Catalog:

Cat. No.: HY-18329
CAS No.: 787632-66-0
Target:  

MDM-2/p53 STAT Apoptosis

Research Areas:  

Cancer

TDP-665759 is an inhibitor for HDm2:p53 complex, and thus activates p53, inhibits STAT3 signaling pathway (EC50 of 5.90 μM) and the cell viability of p53 expressing A549R (IC50 of 7.02 μM). TDP-665759 induces apoptosis in HepG2. TDP-665759 exhibits antitumor efficacy in mouse models .
loading...
    loading...