1 Result for "

TLK286

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TLK286" in MCE Product Catalog:

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Cat. No.: HY-16124
CAS No.: 158382-37-7
Synonyms: TLK-286; TER286
Target:  

DNA-PK Apoptosis

Research Areas:  

Cancer

Canfosfamide (TLK-286, TER286) is a glutathione analogue prodrug that is activated by glutathione S-transferase P1-1 and induces apoptosis. Canfosfamide also inhibits the catalytic kinase activity of DNA-dependent protein kinase (DNA-PK). Canfosfamide produces an anticancer alkylating agent and a glutathione derivative after activation. Canfosfamide can be used to research malignancies .
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