1 Result for "

TM471-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TM471-1" in MCE Product Catalog:

Cat. No.: HY-174129
CAS No.: 2649008-95-5
Target:  

Btk Apoptosis

Research Areas:  

Cancer

TM471-1 is an orally active and covalent Bruton's tyrosine kinase (BTK) inhibitor with IC50 values of 1.3 nM (BTK WT), >40,000 nM (BTK C481S), 7.9 nM (TEC) and 12.4 nM (TXK). TM471-1 inhibits cell growth in vivo and in vitro, arrests cell cycle at G0/G1 phase and induces cell apoptosis .
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