1 Result for "

TML-2Cl

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TML-2Cl" in MCE Product Catalog:

Art. -Nr.: HY-181679
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

TML-2Cl is a dichloro-modified trimethyl lock adapter for antibody-drug conjugates and payload releaser.TML-2Cl undergoes 1,6-elimination followed by rapid self-cyclization to facilitate release of the payload Exatecan after cathepsin B cleavage of the associated linker.TML-2Cl exhibits high stability when conjugated to a drug and high intrinsic hydrophobicity.TML-2Cl can be used for the research of gastric carcinoma .
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