1 Result for "

TMLB-C16

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TMLB-C16" in MCE Product Catalog:

Cat. No.: HY-177796
CAS No.: 2923531-50-2
Target:  

Apoptosis CDK Caspase PARP

Research Areas:  

Cancer

TMLB-C16 is a potent and orally active B3GAT3 inhibitor with a KD of 3.962 μM. TMLB-C16 suppresses proliferation and migration, and induces cell cycle arrest and apoptosis in MHCC-97H (IC50 = 6.53 μM) and HCCLM3 cells (IC50 = 6.22 μM). TMLB-C16 inhibits tumor growth in both MHCC-97H and HCCLM3 xenograft tumor mouse models without causing obvious toxicity. TMLB-C16 can be used for hepatocellular carcinoma research .
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