1 Result for "

TMN-OMe

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TMN-OMe" in MCE Product Catalog:

Cat. No.: HY-182367
Target:  

GPR39

Research Areas:  

Neurological Disease

TMN-OMe is a blood-brain barrier-permeable GPR39 agonist and a radiotracer for positron emission tomography (PET). TMN-OMe activates GPR39 by recruiting β-arrestin, exhibits highly selective binding ability in the mouse brain, and enables quantitative analysis of GPR39 at the in vivo level. TMN-OMe shows specific uptake in GPR39 knockout mice, Alzheimer's disease model (APP/PS1) mice, and blocking experiments. TMN-OMe facilitates in-depth exploration of changes in GPR39-related mechanisms in neurological diseases and is widely used in Alzheimer's disease research .
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