1 Result for "

TNG-917

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TNG-917" in MCE Product Catalog:

Cat. No.: HY-184500
CAS No.: 2923223-81-6
Research Areas:  

Cancer

TNG917 is a potent, selective EHMT1/2 inhibitor with oral activity. TNG917 reduces H3K9me2-mediated transcriptional repression, restores interferon-stimulated gene expression, promotes the secretion of T-cell chemokines such as CXCL10, and converts immunologically cold tumors into T-cell inflamed tumors. TNG917 is applicable to studies on immunologically cold tumors, colorectal cancer, anti-tumor immunity, interferon signaling pathways and epigenetic immune escape .
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