1 Result for "

TNI97

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TNI97" in MCE Product Catalog:

Cat. No.: HY-175030
CAS No.: 2790425-52-2
Research Areas:  

Cancer

TNI-97 is a selective and orally active HDAC6 inhibitor, with an IC50 of 0.2 nM. TNI-97 potently inhibited TNBC cell MDA-MB-453 growth and clonogenicity. TNI-97 induces PANoptosis including apoptosis, necroptosis and pyroptosis in MDA-MB-453 cells. TNI-97 shows antitumor activity in the mice carrying the MDA-MB-453 xenograft or carrying murine-derived TNBC cell allografts. TNI-97 can be used for the study of triple-negative breast cancer .
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