2 Results for "

TO 188

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TO 188" in MCE Product Catalog:

Cat. No.: HY-101810
CAS No.: 82989-25-1
Purity:  99.50%
Synonyms: TO 188; Tazalest; Tazanol
Target:  

Calcium Channel PKC

Research Areas:  

Inflammation/Immunology

Tazanolast (TO 188) is an orally active selective mast cell stabilizer. Tazanolast prevents the elevation of intracellular calcium concentration, inhibits calcium uptake and Protein kinase C translocation, without directly inhibiting phospholipase C. Tazanolast inhibits ozone-induced airway hyperresponsiveness to Methacholine in guinea pigs, as well as passive cutaneous anaphylaxis, Schultz-Dale reaction, experimental asthma, passive cutaneous anaphylaxis in rats, and increased cutaneous vascular permeability in rats. Tazanolast does not alter airway responsiveness in sham-exposed guinea pigs, cell distribution in bronchoalveolar lavage fluid after ozone exposure, type II-IV allergic reactions, or histamine release from atopic leukocytes. Tazanolast can be used in research related to allergic diseases .
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Cat. No.: HY-101810R
CAS No.: 82989-25-1
Synonyms: TO 188 (Standard); Tazalest (Standard); Tazanol (Standard)
Research Areas:  

Inflammation/Immunology

Tazanolast (Standard) (TO 188 (Standard)) is the analytical standard of Tazanolast (HY-101810). This product is intended for research and analytical applications. Tazanolast is a selective mast-cell-stabilizing agent, on ozone-induced airway hyperresponsiveness in guinea pigs.
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