1 Result for "

TO901317

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TO901317" in MCE Product Catalog:

49
49 Cited Publications
Cat. No.: HY-10626
CAS No.: 293754-55-9
Purity:  99.93%
T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXRα . T0901317 activates FXR with an EC50 of 5 μM . T0901317 is RORα and RORγ dual inverse agonist with Ki values of 132 nM and 51 nM, respectively . T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice .
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