1 Result for "

TP0628103 TFA

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TP0628103 TFA" in MCE Product Catalog:

Cat. No.: HY-161169A
CAS No.: 2865106-78-9
Target:  

MMP

Research Areas:  

Cancer

TP0628103 TFA is a potent and highly selective MMP-7 inhibitor with an IC50 of 0.17 nM. TP0628103 TFA undergoes structural optimization via molecular isoelectric point shifting, which reduces organic anion transporter (OAT)-mediated clearance, while maintaining potent MMP-7 inhibitory activity and enhancing MMP subtype selectivity. TP0628103 TFA is applicable for research on the regulatory mechanisms of MMP-7-related matrix metalloproteinases .
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