1 Result for "

TSL2109

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TSL2109" in MCE Product Catalog:

Cat. No.: HY-180574
CAS No.: 2619847-12-8
Target:  

DYRK

Research Areas:  

Cancer

TSL2109 is an orally active and selective DYRK2 and CDK4/6 inhibitor with an IC50 value of 22 nM for DYRK2. TSL2109 exhibits high kinase selectivity over 93%. TSL2109 arrests cell cycle and induces apoptosis in virto. TSL2109 effectively overcomes Enzalutamide (HY-70002) resistance by suppressing tumor growth in vivo and virto. TSL2109 also shows CDK4/6 inhibitor resistance.TSL2109 demonstrates safety profile. TSL2109 can be used for prostate cancer research and breast cancer [1][2].
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