2 Results for "

Top1-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Top1-IN-2" in MCE Product Catalog:

Cat. No.: HY-159935
Target:  

Topoisomerase Apoptosis

Research Areas:  

Cancer

Top1-IN-2 (Compound 1a) is a topoisomerase 1 (Top1) inhibitor. Top1-IN-2 inhibits P-gp resistant tumor cells growth and induces cell apoptosis .
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Cat. No.: HY-184245
CAS No.: 3117528-53-4
Research Areas:  

Cancer

Hsp90-IN-48 is an orally active Hsp90 inhibitor with an IC50 of 19.4 nM. Hsp90-IN-48 improves tumor-cell uptake and intracellular active-component release, and suppresses tumor metastasis. Hsp90-IN-48 induces G2/M phase cell cycle arrest and tumor cell apoptosis whlie simultaneously inhibits Top1/Top2 activity. Hsp90-IN-48 inhibits tumor growth and can be used for colon cancer research .
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