1 Result for "

UCK2 Inhibitor-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "UCK2 Inhibitor-3" in MCE Product Catalog:

Cat. No.: HY-148396
CAS No.: 2376687-49-7
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection Cancer

UCK2 Inhibitor-3 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2, a pyrimidine salvage enzyme) with an IC50 value of 16.6 μM. UCK2 can replace dihydroorotate dehydrogenase (DHODH), in a certain extent, in infected or rapidly dividing cells to continue efficient uridine salvage. UCK2 Inhibitor-3 also inhibits DNA polymerase eta and kappa with IC50s of 56 μM and 16 μM .
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