1 Result for "

UM200

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "UM200" in MCE Product Catalog:

Cat. No.: HY-182923
Target:  

STING

Research Areas:  

Inflammation/Immunology

UM-200 is a covalent STING inhibitor with an EC50 of 1.10 μM. UM-200 covalently modifies the cysteine residues C292 or C309 of STING, thereby blocking its oligomerization and downstream signal transduction. UM-200 inhibits STING-dependent phosphorylation of TBK1 and IRF3. UM-200 inhibits the STING signaling pathway in mouse models. UM-200 can be used for research on STING-driven inflammatory and autoimmune diseases .
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