2 Results for "

UMI-77

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "UMI-77" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-18628
CAS No.: 518303-20-3
Target:  

Bcl-2 Family

Research Areas:  

Cancer

UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
loading...
    loading...
Cat. No.: HY-18628S
UMI-77-d4 is the deuterium labeled UMI-77. UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
loading...
    loading...