1 Result for "

VBI009

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VBI009" in MCE Product Catalog:

Cat. No.: HY-P992158

Target:  

CD47

Research Areas:  

Cancer

VBI-009 is a CD47 and B7-H3 (CD276) bispecific antibody. VBI-009 blocks CD47-SIRPα 'don't eat me' signals and restricts activity to CD47 +/B7-H3 + cells. VBI-009 induces antibody-dependent cellular phagocytosis (ADCP) and antibody-dependent cellular cytotoxicity (ADCC) in CD47 +/B7-H3 + tumor cells. VBI-009 inhibits tumor growth in CD47+/B7-H3+ lung cancer xenograft models. VBI-009 can be used for the research of lung cancer .
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