1 Result for "

VMY-1-101

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VMY-1-101" in MCE Product Catalog:

Cat. No.: HY-182383
CAS No.: 1209002-42-5
Target:  

CDK Apoptosis

Research Areas:  

Cancer

VMY-1-101 is a fluorescent cyclin-dependent kinase (CDK) inhibitor, with an excitation of 410 nm and emission of 512 nm. VMY-1-101 competitively inhibits ATP binding to CDKs. VMY-1-101 induces G2/M cell cycle arrest in human breast cancer cells. VMY-1-101 induces modest apoptosis in human breast cancer cells. VMY-1-101 blocks proliferation of human breast cancer cells, including multidrug resistance-positive cells, and is not a substrate for p-glycoprotein. VMY-1-101 localizes to the cytoplasm of human breast cancer cells. VMY-1-101 shows increased binding to human breast cancer tissue compared to fluorophore alone. VMY-1-101 can be used for the research of breast cancer .
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