1 Result for "

VP19

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VP19" in MCE Product Catalog:

Cat. No.: HY-106122
CAS No.: 105655-99-0
Synonyms: VP 19
Research Areas:  

Cancer

NK-611 (VP 19) is an epipodophyllotoxin derivative. NK-611 induces DNA double-strand breaks by inhibiting topoisomerase II (IC50 = 56 μM). NK-611 does not inhibit microtubule polymerization, thus avoiding the side effects of the parent compound, Podofilox (HY-15552). NK-611 exhibits broad-spectrum antitumor activity and demonstrates potent efficacy in in vivo models of leukemia. NK-611 can be used in cancer research .
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