1 Result for "

VU0364289

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU0364289" in MCE Product Catalog:

Cat. No.: HY-120727
CAS No.: 1242443-29-3
Purity:  99.52%
Target:  

mGluR

Research Areas:  

Neurological Disease

VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM) (binds to the MPEP (HY-14609A) site), with an EC50 of 1.6 μM. VU0364289 shows excellent central nervous system penetration. VU0364289 can reverse amphetamine-induced hyperlocomotion in a dose-dependent manner, which can be used for schizophrenia and other psychiatric research .
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