2 Results for "

Vapitadine

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Vapitadine" in MCE Product Catalog:

Cat. No.: HY-14939
CAS No.: 793655-64-8
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Vapitadine is a non-sedative antihistamine compound that alleviates itching associated with atopic dermatitis.
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Cat. No.: HY-14939A
CAS No.: 279253-83-7
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Vapitadine hydrochloride (Compound 3a) is a selective, orally active and nonsedating antihistamine agent, which exhibits a good binding affinity with human cloned histamine H1 receptor with a Ki of 19 nM. Vapitadine hydrochloride decreases the histamine-induced lethality (ED50 is 0.056-1.2 mg/kg), antagonizes the cutaneous reactions to histamine (ED50 is 0.51-1.4 mg/kg) in rats .
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