3 Results for "

WM266.4

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "WM266.4" in MCE Product Catalog:

Cat. No.: HY-12847
CAS No.: 1163719-91-2
Target:  

Raf Src Apoptosis

Research Areas:  

Cancer

CCT241161 is an orally active pan-RAF inhibitor with IC50s of 3, 6, 10, 15 and 30 nM for LCK, CRAF, SRC, V600E-BRAF and BRAF, respectively. CCT241161 shows good activity to in BRAF and NRAS mutant melanomas. CCT241161 also exhibits anticancer cell proliferative activity .
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Cat. No.: HY-P991609
CAS No.: 561063-60-3

Target:  

MMP

Research Areas:  

Cancer

ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. ABX-MA1 significantly decreases homotypic aggregation and heterotypic adhesion to HUVECs, and the formation of experimental lung metastasis. ABX-MA1 potently inhibits tumor growth, angiogenesis, and MMP-2 expression in A375SM/WM2664 xenograft mice model, promising for melanoma research .
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Cat. No.: HY-145314
Target:  

Integrin

Research Areas:  

Cancer

TC113 is a c(RGDyK)-Based conjugate of Gemcitabine (GEM). TC113 could be internalized by A549 cells through integrin αvβ3. TC113 shows potent antiproliferative properties against WM266.4 and A549 cells .
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