1 Result for "

WRN I852F mutations

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "WRN I852F mutations" in MCE Product Catalog:

Cat. No.: HY-182313
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

WRN-IN-25 is an allosteric Werner syndrome helicase (WRN) inhibitor with an IC50 of 15 nM and a Kd of 54 nM. WRN-IN-25 induces DNA damage, reduces cell viability, and exhibits synthetic lethality in WRN-driven high microsatellite instability cancer cells. WRN-IN-25 can be used in research related to microsatellite instability cancers .
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