1 Result for "

WrFr-OCH3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "WrFr-OCH3" in MCE Product Catalog:

Cat. No.: HY-P11860
Target:  

nAChR

Research Areas:  

Neurological Disease

WrFr-OCH3 is a competitive nAChR inhibitor, with IC50 values of 291.9 nM, 25.3 nM, 477.5 nM and 36.5 nM against hα1β1εδ nAChR, hα9α10 nAChR, hα7 nAChR and hα9 nAChR, respectively. WrFr-OCH3 exhibits analgesic and muscle relaxant effects, reduces forelimb grip strength in rats, and alleviates Oxaliplatin (HY-17371)-induced cold allodynia in rats. WrFr-OCH3 can be used in studies related to cold allodynia .
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