1 Result for "

YCH1899

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YCH1899" in MCE Product Catalog:

Cat. No.: HY-155993
CAS No.: 3032451-66-1
Purity:  99.39%
Target:  

PARP

Research Areas:  

Cancer

YCH1899 is an orally active PARP inhibitor, with an IC50< 0.001 nM for PARP1/2. YCH1899 exhibits distinct antiproliferation activity against Olaparib (HY-10162)-resistant and Talazoparib (HY-16106)-resistant Capan-1 cells (Capan-1/OP and Capan-1/TP cells) , with IC50 values of 0.89 and 1.13 nM, respectively. YCH1899 has acceptable pharmacokinetic properties in rats .
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