1 Result for "

YM116

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YM116" in MCE Product Catalog:

Cat. No.: HY-120067
CAS No.: 183012-13-7
Target:  

Cytochrome P450

Research Areas:  

Endocrinology

YM116 is an orally active and competitive CYP17A1 (17,20-lyase) inhibitor (Ki: 0.38 nM). YM116 reduces the synthesis of adrenal androgens by preferentially inhibiting C17-20 lyase activity. YM116 decreases the serum testosterone concentration, reduces dehydroepiandrosterone sulfate levels and decreases prostatic weights .
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