1 Result for "

YM477-d8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YM477-d8" in MCE Product Catalog:

Cat. No.: HY-13463BS
Synonyms: AKR-501-d8 hydrochloride; E5501-d8 hydrochloride; YM477-d8 hydrochloride
Avatrombopag-d8 (hydrochloride) is deuterium labeled Avatrombopag (hydrochloride). Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A .
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