1 Result for "

ZXH-4-137

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ZXH-4-137" in MCE Product Catalog:

Cat. No.: HY-132862
CAS No.: 2711006-74-3
Target:  

PROTACs

Research Areas:  

Cancer

ZXH-4-137 is a CRBN PROTAC degrader. ZXH-4-137 brings CRBN and VHL E3 ligase into proximity, induces CRBN ubiquitination and proteasomal degradation, and exhibits high selectivity for CRBN. ZXH-4-137 blocks the degradation of CRBN-dependent target proteins such as GSPT1 and CDK9. ZXH-4-137 serves as a chemical knockdown tool compound for investigating CRBN-dependent biological processes .
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