1 Result for "

Zilemaltib

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Zilemaltib" in MCE Product Catalog:

Cat. No.: HY-160698
CAS No.: 2661481-41-8
Synonyms: SGR-1505
Target:  

MALT1 Apoptosis

Research Areas:  

Cancer

SGR-1505 is an oral small molecule MALT1 inhibitor with anti-proliferative and antitumor activity.SGR-1505 inhibits MALT1 enzymatic activity to modulate NF-κB pathway gene expression.SGR-1505 induces modulation of cell cycle, DNA damage, and apoptosis-related genes in in vivo tumor samples.SGR-1505 exerts tumorostatic and regressive activity in ABC-DLBCL xenograft models.SGR-1505 can be used for the research of activated B cell-like diffuse large B cell lymphoma, non-Hodgkin B-cell lymphomas, chronic lymphocytic leukemia, and mature B cell neoplasms .
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