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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
acanthosis
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "acanthosis" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-136527
CAS No.: 2460133-35-9
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Research Areas:
BMS-986251 is an orally active and selective RORγt inverse agonist with an EC50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced (HY-B0180) models (preclinical models of psoriasis) .
Cat. No.: HY-132195
CAS No.: 2672496-70-5
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Research Areas:
RORγt inverse agonist 14 (8e) is a potent, orally active and selective RORγt inverse agonist (EC50 of 2.5 nM) with anti-inflammatory activity. RORγt inverse agonist 14 is used in the study for rheumatoid arthritis and psoriasis .
Cat. No.: HY-122833
CAS No.: 2833703-74-3
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Research Areas:
FGFR3-IN-10 is a selective FGFR3 inhibitor that inhibits FGFR3 kinase activity. FGFR3-IN-10 can be used in research related to cancer, systemic sclerosis, fibrosis, pulmonary fibrosis, achondroplasia, lethal dwarfism, severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN), and Muenke syndrome .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
