FGFR3-IN-10
Based on 1 publication(s) in Google Scholar
FGFR3-IN-10 is a selective FGFR3 inhibitor that inhibits FGFR3 kinase activity. FGFR3-IN-10 can be used in research related to cancer, systemic sclerosis, fibrosis, pulmonary fibrosis, achondroplasia, lethal dwarfism, severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN), and Muenke syndrome.
For research use only. We do not sell to patients.
- CAS No.: 2833703-74-3
- Formula: C23H22ClFN8O2
- Molecular Weight:496.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Publications Citing Use of MedChemExpress (MCE) FGFR3-IN-10
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.93 μM
Compound: 3
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Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISA
Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISA
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[PMID: 31153805] |
Chemical Information
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CAS No. 2833703-74-3
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Molecular Weight 496.92
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Formula C23H22ClFN8O2
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SMILES
OC[C@H](C1=CC=C(C=N1)F)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=N3)C)=CN5C2=C(Cl)C=N5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FGFR3-IN-10 Related Classifications
HY-122833 Related Classifications
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