1 Result for "

castrated macaques

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "castrated macaques" in MCE Product Catalog:

Cat. No.: HY-13699
CAS No.: 352290-60-9
Purity:  98.65%
Target:  

GnRH Receptor PERK

Research Areas:  

Others

NBI-42902 is an orally active, potent functional and competitive antagonist of GnRH receptor with an IC50 value of 0.79 nM, a Ki value of 0.56 nM, respectively. NBI-42902 inhibits GnRH-stimulated inositol phosphate (IP) accumulation, Ca 2+ flux, and ERK1/2 activation. NBI-42902 inhibits serum luteinizing hormone (LH) in castrated male macaques. NBI-42902 can be used for research on sex-hormone-related diseases .
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