5 Results for "

coagulation cascade

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "coagulation cascade" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P991124
CAS No.: 3008610-21-4
Synonyms: REGN-7508

Target:  

Factor XI

Research Areas:  

Cardiovascular Disease

Cenvacibart is a monoclonal antibody with anticoagulant activity, targeting human coagulation factor XI (F11). Cenvacibart blocks the role of coagulation factor XI in the coagulation cascade, reducing thrombus formation. Cenvacibart is promising for research of thrombotic diseases .
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Cat. No.: HY-126944
CAS No.: 4424-17-3
Synonyms: 2-Amino-N-phenylbenzamide
2-Aminobenzamide is a neutral and stable compound used as fluorescent tag, numerously in Glycan analysis. 2-aminobenzamide acts as the starting material for several important reactions like Bargellini reaction as an competent ambident nucleophile. Specifically 2-aminobenzamide and its derivatives are used in the blood coagulation cascade .
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Cat. No.: HY-W743984
Melagatran-d11 is the deuterium labeled Melagatran (HY-129056). Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Melagatran does not require endogenous co-factors for its antithrombin effect and may help to alleviate some of the damaging effects of endotoxemia . Melagatran has the potential to provide a rational approach in the prevention of arterial occlusion .
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Cat. No.: HY-E70393I
Target:  

Others

Research Areas:  

Others

Bovine Factor IXa Beta is an inactive and highly specific enzyme, with a minimal extended substrate recognition site and a preference for particular amino acid residues at specific subsites. Bovine Factor IXa Beta plays a role in the blood coagulation cascade .
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Cat. No.: HY-184684
Target:  

Glycosidase

Research Areas:  

Inflammation/Immunology

HPA-IN-3 (compound 5) is a heparanase (HPA) inhibitor with an IC50 of 11.27 μM against human targets. HPA-IN-3 binds to the active site of HPA, and its structural features enhance binding stability and affinity. HPA-IN-3 reduces the levels of proinflammatory cytokines. HPA-IN-3 maintains organ morphology. HPA-IN-3 improves the survival rate of mice with sepsis induced by cecal ligation and puncture. HPA-IN-3 can be used in studies related to sepsis .
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