2 Results for "

conditionally active biologic (CAB)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "conditionally active biologic (CAB)" in MCE Product Catalog:

Cat. No.: HY-145627
CAS No.: 2460400-11-5
Synonyms: BA3021; Anti-ROR2 ADC; CAB-ROR2-ADC
Ozuriftamab vedotin (BA3021), an antibody-drug conjugate (ADC), is a conditionally active biologic (CAB) anti-receptor tyrosine kinase orphan receptor 2 (ROR2) humanized monoclonal antibody Ozuriftamab (HY-145626) conjugated to VcMMAE (HY-15575). Ozuriftamab vedotin has antitumor activities .
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Cat. No.: HY-P9988
CAS No.: 2460400-28-4
Synonyms: BA301

Research Areas:  

Cancer

Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011) .
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